KLF4-dependent perivascular plasticity contributes to adipose tissue inflammation

OBJECTIVE: Smooth muscle cells and pericytes (SMC-P) display remarkable plasticity during injury and disease progression. Here, we tested the hypothesis that perivascular cells give rise to Klf4-dependent macrophage (MФ)-like cells that augment adipose tissue inflammation and metabolic dysfunction a...

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Vydáno v:Arterioscler Thromb Vasc Biol
Hlavní autoři: Bulut, Gamze B., Alencar, Gabriel F., Owsiany, Katherine M., Nguyen, Anh T., Karnewar, Santosh, Haskins, Ryan M., Waller, Lillian K., Cherepanova, Olga A., Deaton, Rebecca A., Shankman, Laura S., Keller, Susanna R., Owens, Gary K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7769966/
https://ncbi.nlm.nih.gov/pubmed/33054397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.120.314703
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