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KLF4-dependent perivascular cell plasticity mediates pre-metastatic niche formation and metastasis

A deeper understanding of the metastatic process is required for the development of new therapies that improve patient survival. Metastatic tumor cell growth and survival in distant organs is facilitated by the formation of a pre-metastatic niche composed of hematopoietic cells, stromal cells, and e...

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Detalhes bibliográficos
Publicado no:Nat Med
Principais autores: Murgai, Meera, Ju, Wei, Eason, Matthew, Kline, Jessica, Beury, Daniel, Kaczanowska, Sabina, Miettinen, Markku M, Kruhlak, Michael, Lei, Haiyan, Shern, Jack F, Cherepanova, Olga A., Owens, Gary K, Kaplan, Rosandra N
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5724390/
https://ncbi.nlm.nih.gov/pubmed/28920957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4400
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