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KLF4 Dependent Phenotypic Modulation of SMCs Plays a Key Role in Atherosclerotic Plaque Pathogenesis
Herein we employ Myh11-CreER(T2) ROSA floxed STOP eYFP Apoe(−/−) smooth muscle cell (SMC) lineage tracing mice to show that traditional methods for detecting SMCs based on immuno-staining fail to detect > 80% of SMC-derived cells within advanced atherosclerotic lesions. These unidentified SMC-der...
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| Publicado no: | Nat Med |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4552085/ https://ncbi.nlm.nih.gov/pubmed/25985364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3866 |
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