Murine Model of Maternal Immunization Demonstrates Protective Role for Antibodies That Mediate Antibody-Dependent Cellular Cytotoxicity in Protecting Neonates From Herpes Simplex Virus Type 1 and Type 2

BACKGROUND: Neonatal herpes simplex virus (HSV) disease results in unacceptable morbidity and mortality. The primary humoral immune response to natural infection is neutralizing antibodies (Abs). However, Abs that activate Fc gama receptors (FcγRs) and mediate antibody-dependent cell-mediated cytoto...

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Dades bibliogràfiques
Publicat a:J Infect Dis
Autors principals: Kao, Carol M, Goymer, Jessica, Loh, Lip Nam, Mahant, Aakash, Aschner, Clare Burn, Herold, Betsy C
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Major Articles and Brief Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7768689/
https://ncbi.nlm.nih.gov/pubmed/31599942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiz521
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