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Murine Model of Maternal Immunization Demonstrates Protective Role for Antibodies That Mediate Antibody-Dependent Cellular Cytotoxicity in Protecting Neonates From Herpes Simplex Virus Type 1 and Type 2

BACKGROUND: Neonatal herpes simplex virus (HSV) disease results in unacceptable morbidity and mortality. The primary humoral immune response to natural infection is neutralizing antibodies (Abs). However, Abs that activate Fc gama receptors (FcγRs) and mediate antibody-dependent cell-mediated cytoto...

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Bibliografiske detaljer
Udgivet i:J Infect Dis
Main Authors: Kao, Carol M, Goymer, Jessica, Loh, Lip Nam, Mahant, Aakash, Aschner, Clare Burn, Herold, Betsy C
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7768689/
https://ncbi.nlm.nih.gov/pubmed/31599942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiz521
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