HVEM signaling promotes protective antibody-dependent cellular cytotoxicity (ADCC) vaccine responses to herpes simplex viruses

Herpes simplex virus (HSV) glycoprotein D (gD) is required for virus entry and cell-to-cell spread, but also binds the host immunomodulatory molecule, HVEM, blocking interactions with its ligands. Natural infection primarily elicits neutralizing antibodies targeting gD, but subunit protein vaccines...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Sci Immunol
मुख्य लेखकों: Aschner, Clare Burn, Loh, Lip Nam, Galen, Benjamin, Delwel, Isabel, Jangra, Rohit K., Garforth, Scott J., Chandran, Kartik, Almo, Steven, Jacobs, William R., Ware, Carl F., Herold, Betsy C.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2020
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7673108/
https://ncbi.nlm.nih.gov/pubmed/32817296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aax2454
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