HVEM signaling promotes protective antibody-dependent cellular cytotoxicity (ADCC) vaccine responses to herpes simplex viruses

Herpes simplex virus (HSV) glycoprotein D (gD) is required for virus entry and cell-to-cell spread, but also binds the host immunomodulatory molecule, HVEM, blocking interactions with its ligands. Natural infection primarily elicits neutralizing antibodies targeting gD, but subunit protein vaccines...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Sci Immunol
Auteurs principaux: Aschner, Clare Burn, Loh, Lip Nam, Galen, Benjamin, Delwel, Isabel, Jangra, Rohit K., Garforth, Scott J., Chandran, Kartik, Almo, Steven, Jacobs, William R., Ware, Carl F., Herold, Betsy C.
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7673108/
https://ncbi.nlm.nih.gov/pubmed/32817296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aax2454
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires