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Early-Life Stress Alters Synaptic Plasticity and mTOR Signaling: Correlation With Anxiety-Like and Cognition-Related Behavior

Early-life stress (ELS) predisposes individuals to psychiatric disorders, including anxiety and depression, and cognitive impairments later in life. However, the underlying molecular mechanisms are not completely understood. Developmental deficits in hippocampal synaptic plasticity are among the pri...

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Foilsithe in:Front Genet
Main Authors: Wang, Anfeng, Zou, Xiaojuan, Wu, Jiajia, Ma, Qingyu, Yuan, Naijun, Ding, Fengmin, Li, Xiaojuan, Chen, Jiaxu
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7767996/
https://ncbi.nlm.nih.gov/pubmed/33381149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.590068
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