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Early-Life Stress Alters Synaptic Plasticity and mTOR Signaling: Correlation With Anxiety-Like and Cognition-Related Behavior

Early-life stress (ELS) predisposes individuals to psychiatric disorders, including anxiety and depression, and cognitive impairments later in life. However, the underlying molecular mechanisms are not completely understood. Developmental deficits in hippocampal synaptic plasticity are among the pri...

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Pubblicato in:Front Genet
Autori principali: Wang, Anfeng, Zou, Xiaojuan, Wu, Jiajia, Ma, Qingyu, Yuan, Naijun, Ding, Fengmin, Li, Xiaojuan, Chen, Jiaxu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7767996/
https://ncbi.nlm.nih.gov/pubmed/33381149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.590068
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