Matrix Drug Screen Identifies Synergistic Drug Combinations to Augment SMAC Mimetic Activity in Ovarian Cancer

SIMPLE SUMMARY: Recurrent ovarian cancer is difficult to treat due to the development of chemotherapy resistance. This resistance develops through multiple mechanisms to include the avoidance of cell death by cancer cells. Prior studies have shown birinapant, a second mitochondrial activator of casp...

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Pubblicato in:Cancers (Basel)
Autori principali: Noonan, Anne M., Cousins, Amanda, Anderson, David, Zeligs, Kristen P., Bunch, Kristen, Hernandez, Lidia, Shibuya, Yusuke, Goldlust, Ian S., Guha, Rajarshi, Ferrer, Marc, Thomas, Craig J., Annunziata, Christina M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7765376/
https://ncbi.nlm.nih.gov/pubmed/33334024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12123784
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