Intrabone transplantation of CD34(+) cells with optimized delivery does not enhance engraftment in a rhesus macaque model

Intrabone (IB) injection of umbilical cord blood has been proposed as a potential mechanism to improve transplant engraftment and prevent graft failure. However, conventional IB techniques produce low retention of transplanted cells in the marrow. To overcome this barrier, we developed an optimized...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Stringaris, Kate, Hoyt, Robert F., Davidson-Moncada, Jan K., Pantin, Jeremy M., Tisdale, John F., Uchida, Naoya, Raines, Lydia N., Reger, Robert, Sato, Noriko, Dunbar, Cynthia E., Hunt, Timothy J., Clevenger, Randall R., Krouse, Allen, Metzger, Mark E., Bonifacino, Aylin C., Telford, William, Choyke, Peter L., Engels, Theresa, Donahue, Robert E., Childs, Richard W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7757001/
https://ncbi.nlm.nih.gov/pubmed/33351110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003040
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