TWAS pathway method greatly enhances the number of leads for uncovering the molecular underpinnings of psychiatric disorders

Genetic signal detection in genome‐wide association studies (GWAS) is enhanced by pooling small signals from multiple Single Nucleotide Polymorphism (SNP), for example, across genes and pathways. Because genes are believed to influence traits via gene expression, it is of interest to combine informa...

Full description

Saved in:
Bibliographic Details
Published in:Am J Med Genet B Neuropsychiatr Genet
Main Authors: Chatzinakos, Chris, Georgiadis, Foivos, Lee, Donghyung, Cai, Na, Vladimirov, Vladimir I., Docherty, Anna, Webb, Bradley T., Riley, Brien P., Flint, Jonathan, Kendler, Kenneth S., Daskalakis, Nikolaos P., Bacanu, Silviu‐Alin
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Inc. 2020
Subjects:
Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7756231/
https://ncbi.nlm.nih.gov/pubmed/32954640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.32823
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items