Increasing the resolution and precision of psychiatric genome‐wide association studies by re‐imputing summary statistics using a large, diverse reference panel

Genotype imputation across populations of mixed ancestry is critical for optimal discovery in large‐scale genome‐wide association studies (GWAS). Methods for direct imputation of GWAS summary‐statistics were previously shown to be practically as accurate as summary statistics produced after raw geno...

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Pubblicato in:Am J Med Genet B Neuropsychiatr Genet
Autori principali: Chatzinakos, Chris, Lee, Donghyung, Cai, Na, Vladimirov, Vladimir I., Webb, Bradley T., Riley, Brien P., Flint, Jonathan, Kendler, Kenneth S., Ressler, Kerry J., Daskalakis, Nikolaos P., Bacanu, Silviu‐Alin
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Ltd 2021
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8247874/
https://ncbi.nlm.nih.gov/pubmed/33576176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.32834
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