Increasing the resolution and precision of psychiatric genome‐wide association studies by re‐imputing summary statistics using a large, diverse reference panel

Genotype imputation across populations of mixed ancestry is critical for optimal discovery in large‐scale genome‐wide association studies (GWAS). Methods for direct imputation of GWAS summary‐statistics were previously shown to be practically as accurate as summary statistics produced after raw geno...

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Detalhes bibliográficos
Publicado no:Am J Med Genet B Neuropsychiatr Genet
Main Authors: Chatzinakos, Chris, Lee, Donghyung, Cai, Na, Vladimirov, Vladimir I., Webb, Bradley T., Riley, Brien P., Flint, Jonathan, Kendler, Kenneth S., Ressler, Kerry J., Daskalakis, Nikolaos P., Bacanu, Silviu‐Alin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8247874/
https://ncbi.nlm.nih.gov/pubmed/33576176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.32834
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