DISTMIX: direct imputation of summary statistics for unmeasured SNPs from mixed ethnicity cohorts

Motivation: To increase the signal resolution for large-scale meta-analyses of genome-wide association studies, genotypes at unmeasured single nucleotide polymorphisms (SNPs) are commonly imputed using large multi-ethnic reference panels. However, the ever increasing size and ethnic diversity of bot...

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Veröffentlicht in:Bioinformatics
Hauptverfasser: Lee, Donghyung, Bigdeli, T. Bernard, Williamson, Vernell S., Vladimirov, Vladimir I., Riley, Brien P., Fanous, Ayman H., Bacanu, Silviu-Alin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
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Original Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576696/
https://ncbi.nlm.nih.gov/pubmed/26059716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv348
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