JEPEGMIX: gene-level joint analysis of functional SNPs in cosmopolitan cohorts

Motivation: To increase detection power, gene level analysis methods are used to aggregate weak signals. To greatly increase computational efficiency, most methods use as input summary statistics from genome-wide association studies (GWAS). Subsequently, gene statistics are constructed using linkage...

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Pubblicato in:Bioinformatics
Autori principali: Lee, Donghyung, Williamson, Vernell S., Bigdeli, T. Bernard, Riley, Brien P., Webb, Bradley T., Fanous, Ayman H., Kendler, Kenneth S., Vladimirov, Vladimir I., Bacanu, Silviu-Alin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2016
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Applications Notes
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4708106/
https://ncbi.nlm.nih.gov/pubmed/26428293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv567
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