TWAS pathway method greatly enhances the number of leads for uncovering the molecular underpinnings of psychiatric disorders

Genetic signal detection in genome‐wide association studies (GWAS) is enhanced by pooling small signals from multiple Single Nucleotide Polymorphism (SNP), for example, across genes and pathways. Because genes are believed to influence traits via gene expression, it is of interest to combine informa...

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Bibliografiske detaljer
Udgivet i:Am J Med Genet B Neuropsychiatr Genet
Main Authors: Chatzinakos, Chris, Georgiadis, Foivos, Lee, Donghyung, Cai, Na, Vladimirov, Vladimir I., Docherty, Anna, Webb, Bradley T., Riley, Brien P., Flint, Jonathan, Kendler, Kenneth S., Daskalakis, Nikolaos P., Bacanu, Silviu‐Alin
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2020
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7756231/
https://ncbi.nlm.nih.gov/pubmed/32954640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.32823
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