Megakaryocytic Expansion in Gilteritinib-Treated Acute Myeloid Leukemia Patients Is Associated With AXL Inhibition

Numerous recurrent genetic mutations are known to occur in acute myeloid leukemia (AML). Among these common mutations, Fms-like tyrosine kinase 3 remains as one of the most frequently mutated genes in AML. We observed apparent marrow expansion of megakaryocytes in three out of six patients with Flt3...

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Detalles Bibliográficos
Publicado en:Front Oncol
Main Authors: Suknuntha, Kran, Choi, Yoon Jung, Jung, Ho Sun, Majumder, Aditi, Shah, Sujal, Slukvin, Igor, Ranheim, Erik A.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Oncology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7756118/
https://ncbi.nlm.nih.gov/pubmed/33363015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.585151
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