Discovery of survival factor for primitive chronic myeloid leukemia cells using induced pluripotent stem cells

A definitive cure for chronic myeloid leukemia (CML) requires identifying novel therapeutic targets to eradicate leukemia stem cells (LSCs). However, the rarity of LSCs within the primitive hematopoietic cell compartment remains a major limiting factor for their study in humans. Here we show that pr...

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Publicado no:Stem Cell Res
Main Authors: Suknuntha, Kran, Ishii, Yuki, Tao, Lihong, Hu, Kejin, McIntosh, Brian E., Yang, David, Swanson, Scott, Stewart, Ron, Wang, Jean Y.J., Thomson, James, Slukvin, Igor
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003778/
https://ncbi.nlm.nih.gov/pubmed/26561938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2015.10.015
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