Identification of the hemogenic endothelial progenitor and its direct precursor in human pluripotent stem cell differentiation cultures

Hemogenic endothelium (HE) has been recognized as a source of hematopoietic stem cells (HSCs) in the embryo. Access to human HE progenitors (HEPs) is essential to enable the investigation of the molecular determinants of HSC specification. Here we show that HEPs capable of generating definitive hema...

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Bibliografiske detaljer
Main Authors: Choi, Kyung-Dal, Vodyanik, Maxim A., Togaratti, Padma Priya, Suknuntha, Kran, Kumar, Akhilesh, Samarjeet, Fnu, Probasco, Mitchell D., Tian, Shulan, Stewart, Ron, Thomson, James A., Slukvin, Igor I.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462245/
https://ncbi.nlm.nih.gov/pubmed/22981233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.08.002
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