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Optimization of synthetic mRNA for highly efficient translation and its application in the generation of endothelial and hematopoietic cells from human and primate pluripotent stem cells

Identification of transcription factors that directly convert pluripotent stem cells (PSCs) into endothelial and blood cells and advances in the chemical modifications of messenger RNA (mRNA) offer alternative nucleic acid-based transgene-free approach for scalable production of these cells for drug...

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Detalhes bibliográficos
Publicado no:Stem Cell Rev
Main Authors: Suknuntha, Kran, Tao, Lihong, Brok-Volchanskaya, Vera, D’Souza, Saritha S., Kumar, Akhilesh, Slukvin, Igor
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014909/
https://ncbi.nlm.nih.gov/pubmed/29520567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12015-018-9805-1
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