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Optimization of synthetic mRNA for highly efficient translation and its application in the generation of endothelial and hematopoietic cells from human and primate pluripotent stem cells

Identification of transcription factors that directly convert pluripotent stem cells (PSCs) into endothelial and blood cells and advances in the chemical modifications of messenger RNA (mRNA) offer alternative nucleic acid-based transgene-free approach for scalable production of these cells for drug...

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Détails bibliographiques
Publié dans:Stem Cell Rev
Auteurs principaux: Suknuntha, Kran, Tao, Lihong, Brok-Volchanskaya, Vera, D’Souza, Saritha S., Kumar, Akhilesh, Slukvin, Igor
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014909/
https://ncbi.nlm.nih.gov/pubmed/29520567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12015-018-9805-1
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