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Gilteritinib: a novel FLT3 inhibitor for acute myeloid leukemia
FMS-like tyrosine kinase 3- internal tandem duplication (FLT3-ITD) remains as one of the most frequently mutated genes in acute myeloid leukemia (AML), especially in those with normal cytogenetics. The FLT3-ITD and FLT3-TKD (tyrosine kinase domain) mutations are biomarkers for high risk AML and are...
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| Pubblicato in: | Biomark Res |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6737601/ https://ncbi.nlm.nih.gov/pubmed/31528345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40364-019-0170-2 |
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