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Gilteritinib in the treatment of relapsed and refractory acute myeloid leukemia with a FLT3 mutation

Acute myeloid leukemia (AML) is a malignancy of uncontrolled proliferation of immature myeloid blasts characterized by clonal evolution and genetic heterogeneity. FMS-like tyrosine kinase 3 (FLT3) mutations occur in up to a third of AML cases and are associated with highly proliferative disease, sho...

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Detalhes bibliográficos
Publicado no:Ther Adv Hematol
Main Authors: Chew, Serena, Mackey, Melissa C., Jabbour, Elias
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7271272/
https://ncbi.nlm.nih.gov/pubmed/32547718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620720930614
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