Phytosphingosine promotes megakaryocytic differentiation of myeloid leukemia cells

We report that phytosphingosine, a sphingolipid found in many organisms and implicated in cellular signaling, promotes megakaryocytic differentiation of myeloid leukemia cells. Specifically, phytosphingosine induced several hallmark changes associated with megakaryopoiesis from K562 and HEL cells in...

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Detalhes bibliográficos
Publicado no:BMB Rep
Principais autores: Han, Sang Hee, Kim, Jusong, Her, Yerim, Seong, Ikjoo, Park, Sera, Bhattarai, Deepak, Jin, Guanghai, Lee, Kyeong, Chung, Gukhoon, Hwang, Sungkee, Bae, Yun Soo, Kim, Jaesang
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Biochemistry and Molecular Biology 2015
Assuntos:
Research-Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791325/
https://ncbi.nlm.nih.gov/pubmed/26077028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2015.48.12.100
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