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Phytosphingosine promotes megakaryocytic differentiation of myeloid leukemia cells

We report that phytosphingosine, a sphingolipid found in many organisms and implicated in cellular signaling, promotes megakaryocytic differentiation of myeloid leukemia cells. Specifically, phytosphingosine induced several hallmark changes associated with megakaryopoiesis from K562 and HEL cells in...

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Bibliografiske detaljer
Udgivet i:BMB Rep
Main Authors: Han, Sang Hee, Kim, Jusong, Her, Yerim, Seong, Ikjoo, Park, Sera, Bhattarai, Deepak, Jin, Guanghai, Lee, Kyeong, Chung, Gukhoon, Hwang, Sungkee, Bae, Yun Soo, Kim, Jaesang
Format: Artigo
Sprog:Inglês
Udgivet: Korean Society for Biochemistry and Molecular Biology 2015
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791325/
https://ncbi.nlm.nih.gov/pubmed/26077028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2015.48.12.100
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