Rapid, point-of-care molecular diagnostics with Cas13

Rapid nucleic acid testing is a critical component of a robust infrastructure for increased disease surveillance. Here, we report a microfluidic platform for point-of-care, CRISPR-based molecular diagnostics. We first developed a nucleic acid test which pairs distinct mechanisms of DNA and RNA ampli...

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Detalhes bibliográficos
Publicado no:medRxiv
Main Authors: Agrawal, Shreeya, Fanton, Alison, Chandrasekaran, Sita S., Charrez, Bérénice, Escajeda, Arturo M., Son, Sungmin, Mcintosh, Roger, Bhuiya, Abdul, de León Derby, María Díaz, Switz, Neil A., Armstrong, Maxim, Harris, Andrew R., Prywes, Noam, Lukarska, Maria, Biering, Scott B., Smock, Dylan C. J., Mok, Amanda, Knott, Gavin J., Dang, Qi, Van Dis, Erik, Dugan, Eli, Kim, Shin, Liu, Tina Y., Harris, Eva, Stanley, Sarah A., Lareau, Liana F., Tan, Ming X., Fletcher, Daniel A., Doudna, Jennifer A., Savage, David F., Hsu, Patrick D.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7755151/
https://ncbi.nlm.nih.gov/pubmed/33354689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.12.14.20247874
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