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Cyclin D3 drives inertial cell cycling in dark zone germinal center B cells
During affinity maturation, germinal center (GC) B cells alternate between proliferation and somatic hypermutation in the dark zone (DZ) and affinity-dependent selection in the light zone (LZ). This anatomical segregation imposes that the vigorous proliferation that allows clonal expansion of positi...
Sparad:
| I publikationen: | J Exp Med |
|---|---|
| Huvudupphovsmän: | , , , , , , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Rockefeller University Press
2020
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7754672/ https://ncbi.nlm.nih.gov/pubmed/33332554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20201699 |
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