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Germinal center‐derived lymphomas: The darkest side of humoral immunity

One of the unusual features of germinal center (GC) B cells is that they manifest many hallmarks of cancer cells. Accordingly, most B‐cell neoplasms originate from the GC reaction, and characteristically display abundant point mutations, structural genomic lesions, and clonal diversity from the gene...

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Detalhes bibliográficos
Publicado no:Immunol Rev
Main Authors: Mlynarczyk, Coraline, Fontán, Lorena, Melnick, Ari
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6518944/
https://ncbi.nlm.nih.gov/pubmed/30874354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12755
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