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Germinal center‐derived lymphomas: The darkest side of humoral immunity

One of the unusual features of germinal center (GC) B cells is that they manifest many hallmarks of cancer cells. Accordingly, most B‐cell neoplasms originate from the GC reaction, and characteristically display abundant point mutations, structural genomic lesions, and clonal diversity from the gene...

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Bibliographic Details
Published in:Immunol Rev
Main Authors: Mlynarczyk, Coraline, Fontán, Lorena, Melnick, Ari
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6518944/
https://ncbi.nlm.nih.gov/pubmed/30874354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12755
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