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Germinal center‐derived lymphomas: The darkest side of humoral immunity

One of the unusual features of germinal center (GC) B cells is that they manifest many hallmarks of cancer cells. Accordingly, most B‐cell neoplasms originate from the GC reaction, and characteristically display abundant point mutations, structural genomic lesions, and clonal diversity from the gene...

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Dettagli Bibliografici
Pubblicato in:Immunol Rev
Autori principali: Mlynarczyk, Coraline, Fontán, Lorena, Melnick, Ari
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6518944/
https://ncbi.nlm.nih.gov/pubmed/30874354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12755
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