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Germinal center‐derived lymphomas: The darkest side of humoral immunity

One of the unusual features of germinal center (GC) B cells is that they manifest many hallmarks of cancer cells. Accordingly, most B‐cell neoplasms originate from the GC reaction, and characteristically display abundant point mutations, structural genomic lesions, and clonal diversity from the gene...

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Detalles Bibliográficos
Publicado en:Immunol Rev
Autores principales: Mlynarczyk, Coraline, Fontán, Lorena, Melnick, Ari
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6518944/
https://ncbi.nlm.nih.gov/pubmed/30874354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12755
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