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Conformation and Permeability: Cyclic Hexapeptide Diastereomers

Conformational ensembles of eight cyclic hexapeptide diastereomers in explicit cyclohexane, chloroform and water were analyzed by multicanonical molecular dynamics (McMD) simulations. Free energy landscapes (FELs) for each compound and solvent were obtained from the molecular shapes and principal co...

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書目詳細資料
發表在:J Chem Inf Model
Main Authors: Ono, Satoshi, Naylor, Matthew R., Townsend, Chad E., Okumura, Chieko, Okada, Okimasa, Lokey, R. Scott
格式: Artigo
語言:Inglês
出版: 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7751304/
https://ncbi.nlm.nih.gov/pubmed/31042375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.9b00217
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