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Conformation and Permeability: Cyclic Hexapeptide Diastereomers

Conformational ensembles of eight cyclic hexapeptide diastereomers in explicit cyclohexane, chloroform and water were analyzed by multicanonical molecular dynamics (McMD) simulations. Free energy landscapes (FELs) for each compound and solvent were obtained from the molecular shapes and principal co...

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Detalhes bibliográficos
Publicado no:J Chem Inf Model
Main Authors: Ono, Satoshi, Naylor, Matthew R., Townsend, Chad E., Okumura, Chieko, Okada, Okimasa, Lokey, R. Scott
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7751304/
https://ncbi.nlm.nih.gov/pubmed/31042375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.9b00217
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