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Safety and nonclinical and clinical pharmacokinetics of PC945, a novel inhaled triazole antifungal agent
PC945 is a novel antifungal triazole formulated for nebulized delivery to treat lung Aspergillus infections. Pharmacokinetic and safety profiles from nonclinical studies and clinical trials in healthy subjects, and subjects with mild asthma were characterized. Toxicokinetics were assessed following...
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| Pubblicato in: | Pharmacol Res Perspect |
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| Autori principali: | , , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7749516/ https://ncbi.nlm.nih.gov/pubmed/33340279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.690 |
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