Antifungal synergy of a topical triazole, PC945, with a systemic triazole against respiratory Aspergillus fumigatus infection

Invasive pulmonary Aspergillosis is a leading cause of morbidity and mortality in immunosuppressed patients and treatment outcomes using oral antifungal triazoles remain suboptimal. Here we show that combining topical treatment using PC945, a novel inhaled triazole, with systemic treatment using kno...

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Publicat a:Sci Rep
Autors principals: Colley, Thomas, Sehra, Gurpreet, Daly, Leah, Kimura, Genki, Nakaoki, Takahiro, Nishimoto, Yuki, Kizawa, Yasuo, Strong, Pete, Rapeport, Garth, Ito, Kazuhiro
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6603190/
https://ncbi.nlm.nih.gov/pubmed/31263150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45890-w
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