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Safety and nonclinical and clinical pharmacokinetics of PC945, a novel inhaled triazole antifungal agent

PC945 is a novel antifungal triazole formulated for nebulized delivery to treat lung Aspergillus infections. Pharmacokinetic and safety profiles from nonclinical studies and clinical trials in healthy subjects, and subjects with mild asthma were characterized. Toxicokinetics were assessed following...

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書誌詳細
出版年:Pharmacol Res Perspect
主要な著者: Cass, Lindsey, Murray, Alison, Davis, Amanda, Woodward, Kathy, Albayaty, Muna, Ito, Kazuhiro, Strong, Pete, Ayrton, John, Brindley, Charlie, Prosser, Jayne, Murray, John, French, Eddie, Haywood, Phillip, Wallis, Christopher, Rapeport, Garth
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7749516/
https://ncbi.nlm.nih.gov/pubmed/33340279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.690
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