Safety and nonclinical and clinical pharmacokinetics of PC945, a novel inhaled triazole antifungal agent

PC945 is a novel antifungal triazole formulated for nebulized delivery to treat lung Aspergillus infections. Pharmacokinetic and safety profiles from nonclinical studies and clinical trials in healthy subjects, and subjects with mild asthma were characterized. Toxicokinetics were assessed following...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Pharmacol Res Perspect
Main Authors: Cass, Lindsey, Murray, Alison, Davis, Amanda, Woodward, Kathy, Albayaty, Muna, Ito, Kazuhiro, Strong, Pete, Ayrton, John, Brindley, Charlie, Prosser, Jayne, Murray, John, French, Eddie, Haywood, Phillip, Wallis, Christopher, Rapeport, Garth
פורמט: Artigo
שפה:Inglês
יצא לאור: John Wiley and Sons Inc. 2020
נושאים:
Original Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7749516/
https://ncbi.nlm.nih.gov/pubmed/33340279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.690
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