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Regulatory mechanisms of tau protein fibrillation under the conditions of liquid–liquid phase separation

One of the hallmarks of Alzheimer’s disease and several other neurodegenerative disorders is the aggregation of tau protein into fibrillar structures. Building on recent reports that tau readily undergoes liquid–liquid phase separation (LLPS), here we explored the relationship between disease-relate...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Boyko, Solomiia, Surewicz, Krystyna, Surewicz, Witold K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7749306/
https://ncbi.nlm.nih.gov/pubmed/33262278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2012460117
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