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Regulatory mechanisms of tau protein fibrillation under the conditions of liquid–liquid phase separation
One of the hallmarks of Alzheimer’s disease and several other neurodegenerative disorders is the aggregation of tau protein into fibrillar structures. Building on recent reports that tau readily undergoes liquid–liquid phase separation (LLPS), here we explored the relationship between disease-relate...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7749306/ https://ncbi.nlm.nih.gov/pubmed/33262278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2012460117 |
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