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Molecular pathogenesis of spinal bulbar muscular atrophy (Kennedy’s disease) and avenues for treatment

PURPOSE OF REVIEW: To illustrate the current understanding and avenues for developing treatment in spinal and bulbar muscular atrophy (SBMA), an inherited neuromuscular disorder caused by a CAG trinucleotide repeat expansion in the androgen receptor (AR) gene. RECENT FINDINGS: Important advances hav...

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Publicat a:Curr Opin Neurol
Autors principals: Grunseich, Christopher, Fischbeck, Kenneth H.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7748295/
https://ncbi.nlm.nih.gov/pubmed/32773451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WCO.0000000000000856
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