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Spinal and Bulbar Muscular Atrophy Overview
Spinal and bulbar muscular atrophy is an X-linked neuromuscular disease caused by an expanded repeat in the androgen receptor gene. The mutant protein is toxic to motor neurons and muscle. The toxicity is ligand-dependent and likely involves aberrant interaction of the mutant androgen receptor with...
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| Publicado no: | J Mol Neurosci |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5094812/ https://ncbi.nlm.nih.gov/pubmed/26547319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-015-0674-7 |
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