Wordt geladen...
Enantiomer-specific activities of an LRH-1 and SF-1 dual agonist
Chirality is an important consideration in drug development: it can influence recognition of the intended target, pharmacokinetics, and off-target effects. Here, we investigate how chirality affects the activity and mechanism of action of RJW100, a racemic agonist of the nuclear receptors liver rece...
Bewaard in:
| Gepubliceerd in: | Sci Rep |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group UK
2020
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7747700/ https://ncbi.nlm.nih.gov/pubmed/33335203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79251-9 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|