A carregar...
Development of a new class of liver receptor homolog-1 (LRH-1) agonists by photoredox conjugate addition
LRH-1 is a nuclear receptor that regulates lipid metabolism and homeostasis, making it an attractive target for the treatment of diabetes and non-alcoholic fatty liver disease. Building on recent structural information about ligand binding from our labs, we have designed a series of new LRH-1 agonis...
Na minha lista:
| Publicado no: | Bioorg Med Chem Lett |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7701997/ https://ncbi.nlm.nih.gov/pubmed/32631515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2020.127293 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|