Relative contribution of four nucleases, CtIP, Dna2, Exo1 and Mre11, to the initial step of DNA double-strand break repair by homologous recombination in both the chicken DT40 and human TK6 cell lines

Homologous recombination (HR) is initiated by double-strand break (DSB) resection, during which DSBs are processed by nucleases to generate 3' single-strand DNA. DSB resection is initiated by CtIP and Mre11 followed by long-range resection by Dna2 and Exo1 in Saccharomyces cerevisiae. To analyz...

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Библиографические подробности
Опубликовано в: :Genes Cells
Главные авторы: Hoa, Nguyen Ngoc, Akagawa, Remi, Yamasaki, Tomomi, Hirota, Kouji, Sasa, Kentaro, Natsume, Toyoaki, Kobayashi, Junya, Sakuma, Tetsushi, Yamamoto, Takashi, Komatsu, Kenshi, Kanemaki, Masato T., Pommier, Yves, Takeda, Shunichi, Sasanuma, Hiroyuki
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7747012/
https://ncbi.nlm.nih.gov/pubmed/26525166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/gtc.12310
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