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DNA Damage Tolerance Mechanisms Revealed from the Analysis of Immunoglobulin V Gene Diversification in Avian DT40 Cells

DNA replication is an essential biochemical reaction in dividing cells that frequently stalls at damaged sites. Homologous/homeologous recombination (HR)-mediated template switch and translesion DNA synthesis (TLS)-mediated bypass processes release arrested DNA replication forks. These mechanisms ar...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Abe, Takuya, Branzei, Dana, Hirota, Kouji
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6316486/
https://ncbi.nlm.nih.gov/pubmed/30544644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes9120614
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