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DNA damage tolerance by recombination: Molecular pathways and DNA structures

Replication perturbations activate DNA damage tolerance (DDT) pathways, which are crucial to promote replication completion and to prevent fork breakage, a leading cause of genome instability. One mode of DDT uses translesion synthesis polymerases, which however can also introduce mutations. The oth...

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Detalhes bibliográficos
Publicado no:DNA Repair (Amst)
Main Authors: Branzei, Dana, Szakal, Barnabas
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962778/
https://ncbi.nlm.nih.gov/pubmed/27236213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2016.05.008
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