DNA bending facilitates the error-free DNA damage tolerance pathway and upholds genome integrity

DNA replication is sensitive to damage in the template. To bypass lesions and complete replication, cells activate recombination-mediated (error-free) and translesion synthesis-mediated (error-prone) DNA damage tolerance pathways. Crucial for error-free DNA damage tolerance is template switching, wh...

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Detalhes bibliográficos
Main Authors: Gonzalez-Huici, Victor, Szakal, Barnabas, Urulangodi, Madhusoodanan, Psakhye, Ivan, Castellucci, Federica, Menolfi, Demis, Rajakumara, Eerappa, Fumasoni, Marco, Bermejo, Rodrigo, Jentsch, Stefan, Branzei, Dana
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983681/
https://ncbi.nlm.nih.gov/pubmed/24473148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201387425
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