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SUMO-Chain-Regulated Proteasomal Degradation Timing Exemplified in DNA Replication Initiation
Similar to ubiquitin, SUMO forms chains, but the identity of SUMO-chain-modified factors and the purpose of this modification remain largely unknown. Here, we identify the budding yeast SUMO protease Ulp2, able to disassemble SUMO chains, as a DDK interactor enriched at replication origins that prom...
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| Udgivet i: | Mol Cell |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cell Press
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6891891/ https://ncbi.nlm.nih.gov/pubmed/31519521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.08.003 |
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