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Nontarget Analysis Reveals Gut Microbiome-dependent Differences in the Fecal PCB Metabolite Profiles of Germ-Free and Conventional Mice

Mammalian polychlorinated biphenyl (PCB) metabolism has not been systematically explored with nontarget high-resolution mass spectrometry (Nt-HRMS). Here we investigated the importance of the gut microbiome in PCB biotransformation by Nt-HRMS analysis of feces from conventional (CV) and germ-free (G...

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Detalhes bibliográficos
Publicado no:Environ Pollut
Main Authors: Li, Xueshu, Liu, Yanna, Martin, Jonathan W., Cui, Julia Yue, Lehmler, Hans-Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7746632/
https://ncbi.nlm.nih.gov/pubmed/33032095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.envpol.2020.115726
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