NMN Rescues Endothelial Function and Neurovascular Coupling, Improving Cognitive Function in Aged Mice

Adjustment of cerebral blood flow (CBF) to neuronal activity via neurovascular coupling (NVC) has an essential role in maintenance of healthy cognitive function. In aging increased oxidative stress and cerebromicrovascular endothelial dysfunction impair NVC, contributing to cognitive decline. There...

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Published in:Innov Aging
Main Authors: Tarantini, Stefano, Yabluchanskiy, Andriy, Ballabh, Praveen, Farkas, Eszter, Baur, Joseph, Sinclair, David, Csiszar, Anna, Ungvari, Zoltan
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7741797/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igaa057.399
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