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Treatment with the mitochondrial‐targeted antioxidant peptide SS‐31 rescues neurovascular coupling responses and cerebrovascular endothelial function and improves cognition in aged mice

Moment‐to‐moment adjustment of cerebral blood flow (CBF) via neurovascular coupling has an essential role in maintenance of healthy cognitive function. In advanced age, increased oxidative stress and cerebromicrovascular endothelial dysfunction impair neurovascular coupling, likely contributing to a...

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書目詳細資料
發表在:Aging Cell
Main Authors: Tarantini, Stefano, Valcarcel‐Ares, Noa M., Yabluchanskiy, Andriy, Fulop, Gabor A., Hertelendy, Peter, Gautam, Tripti, Farkas, Eszter, Perz, Aleksandra, Rabinovitch, Peter S., Sonntag, William E., Csiszar, Anna, Ungvari, Zoltan
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5847870/
https://ncbi.nlm.nih.gov/pubmed/29405550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12731
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