Treatment with the mitochondrial‐targeted antioxidant peptide SS‐31 rescues neurovascular coupling responses and cerebrovascular endothelial function and improves cognition in aged mice

Moment‐to‐moment adjustment of cerebral blood flow (CBF) via neurovascular coupling has an essential role in maintenance of healthy cognitive function. In advanced age, increased oxidative stress and cerebromicrovascular endothelial dysfunction impair neurovascular coupling, likely contributing to a...

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Detaylı Bibliyografya
Yayımlandı:Aging Cell
Asıl Yazarlar: Tarantini, Stefano, Valcarcel‐Ares, Noa M., Yabluchanskiy, Andriy, Fulop, Gabor A., Hertelendy, Peter, Gautam, Tripti, Farkas, Eszter, Perz, Aleksandra, Rabinovitch, Peter S., Sonntag, William E., Csiszar, Anna, Ungvari, Zoltan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2018
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5847870/
https://ncbi.nlm.nih.gov/pubmed/29405550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12731
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