Cerebromicrovascular dysfunction predicts cognitive decline and gait abnormalities in a mouse model of whole brain irradiation-induced accelerated brain senescence

Whole brain irradiation (WBI) is a mainstream therapy for patients with both identifiable brain metastases and prophylaxis for microscopic malignancies. However, it also promotes accelerated senescence in healthy tissues and leads to progressive cognitive dysfunction in up to 50% of tumor patients s...

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Detaylı Bibliyografya
Yayımlandı:GeroScience
Asıl Yazarlar: Ungvari, Zoltan, Tarantini, Stefano, Hertelendy, Peter, Valcarcel-Ares, M. Noa, Fülöp, Gabor A., Logan, Sreemathi, Kiss, Tamas, Farkas, Eszter, Csiszar, Anna, Yabluchanskiy, Andriy
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer International Publishing 2017
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352588/
https://ncbi.nlm.nih.gov/pubmed/28299642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-017-9964-z
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